PUBLICATIONS
Choe, E. Optimizing Video for Learning: A Case Study-Based Primer of Informal, Educational, Digital Video Best Practices (2017). Available at SSRN: https://ssrn.com/abstract=2909769 or http://dx.doi.org/10.2139/ssrn.2909769
Through case studies of existing digital educational videos, this paper attempts to connect, curate, and distill best practices that have emerged from learning sciences research, educational video use, and video production. It is a review of educational, online video best practices and research as of early-2017, written especially for producers and educators who are interested in using video to communicate technical content and to facilitate learning.
Choe, E. Video Production as a Pathway for Building Identity (2017). Available at SSRN: https://ssrn.com/abstract=2969114 or http://dx.doi.org/10.2139/ssrn.2969114
How can educators use informal video production to facilitate educational, creative processes for students? What are effective approaches in teaching digital media production and literacy and what skills are best built by these creative processes? This analysis traces the successes and failures of three years of a month-long course for MIT students to script and host science, technology, engineering, and/or math-related YouTube videos to inspire youth and facilitate meaningful learning. This in-depth case study unpacks our instructional approach for and outcomes from equipping STEM-inclined students to become inspiring advocates for their fields.
Choe, E. Determining "Success" for Online Educational Videos (2015). Available at https://medium.com/@echoewrites/determining-success-for-online-educational-videos-9850d7b0da5a
Pre-teen girls and middle-aged men ended up watching the same educational video — this is why it should affect how we look at video as a learning experience.
Kazmierczak, R., Choe, E., Sinclair, J., Eisenstark, A. Direct Attachment of Nanoparticle Cargo to Salmonella typhimurium Membranes Designed for Combination Bacteriotherapy Against Tumors (2015). Methods in Molecular Biology, Vol. 1225 pg. 151-163. https://www.ncbi.nlm.nih.gov/pubmed/25253255
Nanoparticles hold promise for cancer treatment due to the innate ability of certain nanoparticles to accumulate in the porous environment of tumors and to be toxic to cancer cells. However, the therapeutic success of nanoparticles is limited by the physical difficulty of fully penetrating and attacking tumors. Plus, while they can target tumors, it's difficult to tailor the delivery of nanoparticles or drugs to targets in other diseases, like cardiac disease. Thus, a need for delivery systems that will accurately and precisely bring nanoparticles carrying drug payloads to their intended sites currently exists. Our solution to this engineering challenge is to load such nanoparticles onto a biological "mailman" (a novel, nontoxic, therapeutic strain of Salmonella typhimurium engineered to preferentially and precisely seek out, penetrate, and hinder prostate cancer cells as the biological delivery system) that will deliver the therapeutics to a target site.
Choe, E., Kazmierczak, R., Eisenstark, A. Phenotypic Evolution of Therapeutic Salmonella enterica Serovar Typhimurium after Invasion of TRAMP Mouse Prostate Tumor (2014). mBio Vol. 5, No. 4. http://mbio.asm.org/content/5/4/e01182-14
Salmonella has been of interest in cancer research due to its intrinsic ability to selectively target and colonize within tumors, leading to tumor cell death. Current research indicates promising use of Salmonella to remove tumors in mouse models while minimizing toxic side effects. However, selection of mutants during such long-term tumor colonization is a safety concern, and understanding how the population of injected Salmonella mutates or is selected within a tumor is an important consideration in predicting the long-term success of bacterium-based cancer treatment strategies. This is our initial examination of selected phenotypes in a therapeutic Salmonella strain developed from an archival wild-type LT2 strain and injected into 6-month-old TRAMP (transgenic adenocarcinoma of mouse prostate) mice.